What does the TV show Castle have to do with the biggest convention in the world for celebrating all things science fiction, fantasy, superhero, comic book, etc.? Absolutely nothing. The show is a mainstream detective drama/comedy with none of those elements.
So why did they have the cast of the show at the 2011 convention? Because Nathan Fillion has a huge fan following from a prior science fiction show he did called Firefly. You may not have heard of it, but in the few short years since it went off the air it has probably amassed the third largest set of fans in the Comic Con community – behind only Star Trek and Star Wars.
Their appearance at the 2010 convention was a big hit so they returned in 2011. The following four videos are the complete 50 minute panel that the cast held at Comic Con 2011. Unfortunately, Stana Katic could not make it for this panel, but it does have Nathan Fillion (Castle), Jon Huertas (Esposito), Seamus Dever (Ryan), Molly Quinn (Alexis), and Tamala Jones (Lanie).